HOW CAN WE USE THIS? 

Katie Witkiewitz, et.al. (2023) returned to the databases of foundational research, COMBINE (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945872/) and Project MATCH (https://www.niaaa.nih.gov/news-events/news-releases/niaaa-reports-project-match-main-findings), to view it through the lens of the Alcohol and Addiction Research Domain Criteria (AARDoC, Litten, et.al. 2015). This was an attempt to see if the criteria can predict outcomes and inform the development of a pragmatic instrument to guide alcohol use disorder treatment planning.  Their efforts are in the spirit of precision medicine, or identifying treatments that target elements specific to the person in treatment.  The domains, that fall on a trajectory of severity (reward/incentive salience, relief/negative emotionality, and loss of control/executive functioning), also speak to the motivations for alcohol use and suggest potential targets for intervention; e.g. alternatives for rewards, emotional improvement, and cognitive behavioral functioning respectively.  The domains may also be relevant to the trajectory of other use disorders and thus have applicability that is more general.  The self-report items that mapped to the domains are in the Witkiewitz, et.al. (2023) article (https://psycnet.apa.org/doiLanding?doi=10.1037%2Fadb0000871) and they might serve to draft an instrument for trying out the concept and perhaps eventual validation.